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Everolimus inhibits Helicobacter pylori-induced expression and secretions of IL-6, TNF-α, and <t>IL-8.</t> (a-c). mRNA of IL-6, TNF-α, IL-8; (d). Secretions of IL-6; (e). Secretions of TNF-α; (f). Secretions of IL-8 (####, P < 0.0001 vs. vehicle group;$, P < 0.01, 0.001 vs. Helicobacter pylori group, N = 5).
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Everolimus inhibits Helicobacter pylori-induced expression and secretions of IL-6, TNF-α, and IL-8. (a-c). mRNA of IL-6, TNF-α, IL-8; (d). Secretions of IL-6; (e). Secretions of TNF-α; (f). Secretions of IL-8 (####, P < 0.0001 vs. vehicle group;$, P < 0.01, 0.001 vs. Helicobacter pylori group, N = 5).

Journal: Bioengineered

Article Title: Everolimus ameliorates Helicobacter pylori infection-induced inflammation in gastric epithelial cells

doi: 10.1080/21655979.2021.2018533

Figure Lengend Snippet: Everolimus inhibits Helicobacter pylori-induced expression and secretions of IL-6, TNF-α, and IL-8. (a-c). mRNA of IL-6, TNF-α, IL-8; (d). Secretions of IL-6; (e). Secretions of TNF-α; (f). Secretions of IL-8 (####, P < 0.0001 vs. vehicle group;$, P < 0.01, 0.001 vs. Helicobacter pylori group, N = 5).

Article Snippet: Elisa kits from R&D system were used: IL-6 (#D7050,), TNF-α (#DTA00D), IL-8 (#S8000C), CXCL1 (# SGR00B), CCL2 (# SCP00), and ICAM-1 (#SCIM00).

Techniques: Expressing